Category: Theoretical and Computational Biophysics

Binding mechanism and distant regulation of histone deacetylase 8 by PCI-34051

Dynamics of the mammalian pyruvate dehydrogenase complex revealed by in-situ structural analysis

Dissecting the Roles of Electrostatic Interactions in Modulating the Folding Stability and Cooperativity of Engrailed Homeodomain

Fluctuating Chromatin Facilitates Enhancer–Promoter Communication by Regulating Transcriptional Clustering Dynamics

Unraveling the Interplay between Stability and Flexibility in the Design of Polyethylene Terephthalate (PET) Hydrolases

Balancing thermodynamic stability, dynamics, and kinetics in phase separation of intrinsically disordered proteins

Redesigned Guide DNA Enhanced Clostridium butyricum Argonaute Activity for Amplification-Free and Multiplexed Detection of Pathogens

Deciphering the dynamical chromosome structural reorganizations in human neural development

Computational and Chemical Design Strategy for Manipulating Glycan‐Protein Recognition

Quantifying the large-scale chromosome structural dynamics during the mitosis-to-G1 phase transition of cell cycle