Category: Theoretical and Computational Biophysics

Large-scale data-driven and physics-based models offer insights into the relationships among the structures, dynamics, and functions of the chromosomes

Insights into the cell fate decision-making processes from chromosome structural reorganizations

Quantifying chromosome structural reorganizations during the differentiation, reprogramming and transdifferentiation

Insights into phosphorylation induced protein allostery and conformational dynamics of Glycogen Phosphorylase via integrative structural mass spectrometry and in silico modeling

Uncovering the quantitative relationships among chromosome fluctuations, epigenetics, and gene expressions of transdifferentiation on Waddington landscape

Investigating the conformational dynamics of a Y-family DNA polymerase during its folding and binding to DNA and a nucleotide

Dynamics and pathways of chromosome structural organizations during cell transdifferentiation

Molecular Simulations of Intrinsically Disordered Proteins and Their Binding Mechanisms

Advanced Sampling and Modeling in Molecular Simulations for Slow and Large-Scale Biomolecular Dynamics

Physics of biomolecular recognition and conformational dynamics