Theoretical and Computational Biophysics

Computational and Chemical Design Strategy for Manipulating Glycan‐Protein Recognition

Advanced Science, 11(24), 2308522, 2024.

Qiang Zhu, Didi Geng, Jingchao Li, Jinqiu Zhang, Haofan Sun, Zhiya Fan, Jiahui He, Ninghui Hao, Yinping Tian, Liuqing Wen, Tiehai Li, Weijie Qin, Xiakun Chu, Yong Wang*, Wen Yi*.

Quantifying the large-scale chromosome structural dynamics during the mitosis-to-G1 phase transition of cell cycle

Open Biology, 13(11), 230175, 2023

Xiakun Chu and Jin Wang*.

Large-scale data-driven and physics-based models offer insights into the relationships among the structures, dynamics, and functions of the chromosomes

Journal of Molecular Cell Biology, 15(6), mjad042, 2023

Cibo Feng, Jin Wang* and Xiakun Chu*.

Insights into the cell fate decision-making processes from chromosome structural reorganizations

Biophysics Reviews, 3(4), 041402, 2022

Xiakun Chu and Jin Wang*.

Quantifying chromosome structural reorganizations during the differentiation, reprogramming and transdifferentiation

Physical Review Letters, 129(6), 068102, 2022.

Xiakun Chu and Jin Wang*.

Insights into phosphorylation induced protein allostery and conformational dynamics of Glycogen Phosphorylase via integrative structural mass spectrometry and in silico modeling

ACS Chemical Biology, 17(7), 1951-1962, 2022

Jing Huang+, Xiakun Chu+ (co-first), Yuxiang Luo+, Yong Wang, Ying Zhang, Yu Zhang, and Huilin Li*.

Uncovering the quantitative relationships among chromosome fluctuations, epigenetics, and gene expressions of transdifferentiation on Waddington landscape

Advanced Science, 9(10), 2103617, 2022.

Wenting Chu, Xiakun Chu, and Jin Wang*.

Investigating the conformational dynamics of a Y-family DNA polymerase during its folding and binding to DNA and a nucleotide

JACS Au, 2(2), 341-356, 2022.

Xiakun Chu, Zucai Suo and Jin Wang*.